The Icahn School of Medicine is one of the nation’s elite medical schools and provides the largest training ground in the United States for clinical residents and fellows. The Graduate School of Biomedical Sciences is tightly integrated with the research enterprise and supports exceptional training for PhD and master’s students, while the Mount Sinai Phillips School of Nursing offers state-of-the-art training for nurses, embedded within one of the largest health systems in the world.
The real-world potential of artificial intelligence (AI) emerged this past year in a way never before seen. We describe the many ways we are harnessing this technology on our AI at Mount Sinai digital hub. Here are some notable examples:
Infused by large sets of genomic and clinical data, AI supercharges Mount Sinai’s life-changing research. The Mount Sinai Health System, ranked No. 1 on the new Nature AI Index 2024 list of “Leading 10 Healthcare Institutions” for AI across all fields by the prestigious journal Nature, is a recognized leader in realizing the impact AI will have on human health. Powered by one of the world’s most diverse clinical datasets, Mount Sinai is uniquely positioned to leverage AI to answer some of humanity’s most quintessential questions, reveal the origins of health and disease at unprecedented resolution, and catapult us into a new era of personalized medicine.
No. 1
on the new Nature AI Index 2024 list of
“Leading 10 Healthcare Institutions” for AI across all fields
At Mount Sinai, AI is more than a tool—it’s a partner, carefully trained and monitored, that empowers us to model a learning health system where every patient (with their consent) is a research participant. This technology allows us to optimize care in real time, leading to ever-improving care for the next patient. We already possess one of the largest biobanks in the world, and the Mount Sinai Million Health Discoveries Program will soon sequence the genomes of 1 million Mount Sinai patients. These initiatives make it possible to integrate multimodal data at the population level and then translate discoveries into interventions at the individual level—the very definition of personalized medicine. Our emphasis on population- and community-based research ensures that this kind of optimal care delivery will be not just for the few, but for everyone.
$500M
received from the NIH in fiscal year 2025
$875M
in total research funding in calendar year 2025
Despite national funding challenges, our National Institutes of Health (NIH) research funding remained strong, with more than $500 million in fiscal year 2025 and $875 million in total research funding in calendar year 2025. As the backbone of the scientific endeavor, this grant funding, combined with philanthropic giving, resulted in breakthroughs across disciplines that I encourage you to learn about in our press releases and themed booklets published biannually in Science, highlighting such areas as cancer, brain science, artificial intelligence, immunology, women’s health, and the heart.
In Our Students’ Own Words
Brooke Friedman
What experience in 2025 most shaped your growth as a physician or scientist?
“In October 2025, I was honored to serve as a keynote speaker for 900 attendees at the National Organization for Rare Disorders annual conference. This experience not only strengthened my scientific communication skills but also allowed me to directly engage with rare disease patients. Now, I have a firsthand perspective of how my work as a basic scientist is foundational to the larger goal of improving patient lives.”
–Brooke Friedman
Neuroscience PhD Student
Timothy Hoang, left, and Lathan Liou, MPhil
“During my rotation on the labor and delivery floor, I had the opportunity to be in the operating room for a C-section, witnessing a birth for the first time. It was an unforgettable and moving moment. I found myself tearing up, not only because I was witnessing new life being brought into the world, but also because I was grateful that the family allowed me to be present during such an intimate moment. I really value these moments and the relationships we build with our patients.”
–Timothy Hoang
MD Student, Third Year
“During my internal medicine acting internship, I took care of a patient who required me to use the entire breadth of my medical education: practicing fundamental physical exams, managing complex comorbidities across organ systems, using palliative empathy, and wrestling with ethical challenges. This experience reminded me that the study of medicine is lifelong, and the art of it will be a goal to always strive toward.”
–Lathan Liou, MPhil
MD Student, Fourth Year