The facility also has a high-end centralized workstation for image processing, high performance computing (HPC) (for example, deep learning), and big-data storage, and also provides access to several commercial software programs for image analysis and data quantification.
![](https://downloads.ctfassets.net/iujm5coq335o/5S632pL2xAdd5bXOkkEVBb/ac86a57c8ec60b1e774eb0942f45845b/-FBIfall2022-07-_Image-1.gif?fm=webp)
The Brain in Action
Cleared mouse brain stained for FOS (red channel, marks activated neurons); CD31 (green channel, marks vasculature epithelium); and autofluorescence (gray channel, shows general brain structure). Rendered surfaces and used slicers over volumetric images showcase some basic functionality of Mount Sinai’s 3D rendering program.
Credit:
Nikolaos Tzavaras, PhD, Assistant Professor, Department of Neuroscience, and Operations Manager, Microscopy and Advanced Bioimaging CoRE
Dr. Tzavaras is developing image acquisition and analysis strategies for whole-organ imaging and extracting correlative imaging data using different microscopy modalities on the same samples. Additionally, he is developing image registration, segmentation, and analysis pipelines to automate data extraction.